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DNA molecules and vectors regarding clavulanic aci

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专利名称:DNA molecules and vectors regarding

clavulanic acid biosynthesis enzymes

发明人:John Edward Hodgson,Alison Jane Earl申请号:US08/159950申请日:19931201公开号:US05759831A公开日:19980602

摘要:DNA sequences obtained from S. clavuligerus, recombinant vectors

incorporating such sequences and hosts transformed with such vectors are disclosed. TheDNA comprises one or more genes encoding one or more enzymes involved in thebiosynthesis of clavulanic acid and may be used to improve the yield of clavulanic acidproduced by clavulanic acid- producing organisms such as S. clavuligerus ATCC 270.

申请人:BEECHAM GROUP P.L.C.

代理机构:Hopgood Calimafde Kalil & Judlowe LLP

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